Hydrogels with Brain Tissue-Like Mechanical Properties in Complex Environments

Mechanical properties of brain tissue in tension.

This paper contains experimental results of in vitro, uniaxial tension of swine brain tissue in finite deformation as well as proposes a new hyper-viscoelastic constitutive model for the brain tissue. The experimental results obtained for two loading velocities, corresponding to strain rates of 0.64 and 0.64 x 10(-2)s(-1), are presented. We believe that these are the first ever experiments of t...

characterizing the mechanical properties of rat brain tissue in tension

background: characterizing the mechanical properties of brain tissue is deemed important for developing a comprehensive knowledge of the mechanisms underlying brain diseases. mechanical properties of very soft tissues, such as brain until recently have been attracted the attention of researchers because these tissues do not tolerate mechanical loads. the mechanical properties of brain tissue, h...

Dynamic mechanical properties of human brain tissue.

Investigators have been studying the mechanical phenomena associated with impact to the head for many years. Several theories on the behavior of the brain during head impact have come from these studies but there has been a notable lack of information on the bulk mechanical properties of the brain which are necessary for the evaluation of these theories. This paper represents an initial attempt...

Mechanical Characterisation of Hydrogels for Tissue Engineering

Emerging properties of hydrogels in tissue engineering

Hydrogels are three-dimensional polymeric networks filled with water and mimic tissue environments. Therefore, they are considered optimal to deliver cells and engineer damaged tissues. The hydrogel networks have been significantly modified to endow biochemical functionality with adhesive ligands, growth factors, or degradable sites that are helpful to drive proper cell functions. Recently, som...